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Mohane Coumar

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My group's research involves application of Computer-aided drug design techniques for drug discovery. Major focus of research is on Cancer drug discovery.
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Sl. NoAuthorsTitleJournalYear of PublicationVolume and Page No
71Ashok Sharma, Badvel Pallavi, Riddhidev Banerjee, Mariasoosai Ramya Chandar Charles, Mohane Selvaraj Coumar, Subhash Chander, Murugesan Sankaran, Paritosh ShuklaDe novo Design and in-silico Studies of Coumarin Derivatives as Inhibitors of Cyclin Dependent Kinase-2Journal of Pharmaceutical Chemistry20174, 46-56
70Syed SB, Arya H, Fu IH, Yeh TK, Periyasamy L Hsieh HP, Coumar MS*Targeting P-glycoprotein: Investigation of piperine analogs for overcoming drug resistance in cancerScientific reports20177(1):7972
69Singh P, Sailu S, Palchamy E, Coumar MS, Baluchamy SIdentification of a novel leukemic-specific splice variant of DNMT3B and its stability.Medical Oncology201734(8):145.
68Mamta Verma, Ramya Chandar Charles. M, Baskar Chakrapani, Mohane Selvaraj Coumar, Gayathri Govindaraju, Arumugam Rajavelu, Sreenivas Chavali & Arunkumar Dhayalan.PRMT7 INTERACTS WITH ASS1 AND CITRULLINEMIA MUTATIONS DISRUPT THE INTERACTION.J. Molecular Biology2017429(15), 2278-2289
67Hemant Arya, Safiulla Basha Syed, Sorokhaibam Sureshkumar Singh, Dinakar R. Ampasala and Mohane Selvaraj Coumar*.INVESTIGATIONS OF CHEMICAL CONSTITUENTS OF CLERODENDRUM COLEBROOKIANUM IN ANTI-HYPERTENSIVE DRUG TARGETS USING DOCKING AND MOLECULAR DYNAMICS SIMULATIONSInterdisciplinary Sciences: Computational Life Sciences2017
66Vivek Kumar Singh and Mohane Selvaraj Coumar*ENSEMBLE-BASED VIRTUAL SCREENING: IDENTIFICATION OF POTENTIAL ALLOSTERIC INHIBITOR OF BCR-ABLJ Moecular Modeling201723 (7), 218
65Larance Ronsard, Nilanjana Ganguli, Vivek Kumar Singh, Kumaravel Mohankumar, Tripti Rai, Subhashree Sridharan, Sankar Pajaniradje, Binod Kumar, Suhnrita Chaudhuri, Mohane Selvaraj Coumar, Vishnampettai G Ramachandran and Akhil C Banerjea. IMPACT OF GENETIC VARIATIONS IN HIV-1 TAT ON LTR-MEDIATED TRANSCRIPTION VIA TAR RNA INTERACTION: EMERGENCE OF VIRULENT STRAINS AMONG HIV-1 INFECTED NORTH INDIANS. Frontiers. Microbiology20178:706
64Gopichand Chinta, Mohane Selvaraj Coumar and Latha Periyasamy. REVERSIBLE TESTICULAR TOXICITY OF PIPERINE ON MALE ALBINO RATS. Pharmacognosy Magazine201713 (Suppl 3), S525
63Phanikrishna P, Sailu Sarvagalla, Bindu Madhuri, Sankar Pajaniradje, Vinitha Baskaran, Mohane Selvaraj Coumar, & R. Baskaran. IDENTIFICATION OF NATURAL INHIBITORS OF BCR-ABL FOR THE TREATMENT OF CHRONIC MYELOID LEUKEMIA. Chemical Biology
& Drug Design.
201790(4):596-608
62Shamim Akhtar Sufi, Lakshmi Narayana Adigopula, Safiulla Basha Syed, Victor Mukherjee, Mohane S. Coumar, H. Surya Prakash Rao and Rukkumani RajagopalanIN-SILICO AND IN-VITRO ANTI-CANCER POTENTIAL OF A CURCUMIN ANALOGUE (1E, 6E)-1, 7-DI (1H-INDOL-3-YL) HEPTA-1, 6-DIENE-3, 5-DIONEBiomedicine & Pharmacotherapy201785, 389–398
61Vivek Kumar Singh, Hsin-Huei Chang, Ching-Chuan Kuo, Hui-Yi Shiao, Hsing-Pang Hsieh and Mohane Selvaraj Coumar*DRUG REPURPOSING FOR CHRONIC MYELOID LEUKEMIA: IN SILICO AND IN VITRO INVESTIGATION OF DRUGBANK DATABASE FOR ALLOSTERIC BCR-ABL INHIBITORS.J. Biomolecular Structure Dynamics201735 (8), 1833-1848
60Yung Chang Hsu, Mohane Selvaraj Coumar, Wen-Chieh Wang, Hui-Yi Shiao, Yi-Yu Ke, Wen-Hsing Lin, Ching-Chuan Kuo, Chun-Wei Chang, Fu-Ming Kuo, Pei-Yi Chen, Sing-Yi Wang, An-Siou Li, Chun-Hwa Chen, Po-Chu Kuo, Ching-Ping Chen, Ming-Hsine Wu, Chen-Lung Huang, Kuei-Jung Yen, Yun-I Chang, John Tsu-An Hsu, Chiung-Tong Chen, Teng-Kuang Yeh, Jen-Shin Song, Chuan Shih and Hsing-Pang HsiehDISCOVERY OF BPR1K871 - A QUINAZOLINE BASED MULTI-KINASE INHIBITOR FOR THE TREATMENT OF AML AND SOLID TUMORS: RATIONAL DESIGN, SYNTHESIS, IN VITRO AND IN VIVO EVALUATIONOncotarget 20167, 86239-86256
59Sarvagalla, S.; Cheung, C.H.A.; Tsai, J.Y.; Hsieh, H.P.; Coumar, M.S*
DISRUPTION OF PROTEIN-PROTEIN INTERACTIONS: HOT SPOT DETECTION, STRUCTURE-BASED VIRTUAL SCREENING AND IN VITRO TESTING FOR THE ANTI-CANCER DRUG TARGET - SURVIVIN.RSC Advances20166, 31947-31959
58Dinakar R. Ampasala, M. Pritika, Mohane Selvaraj Coumar and Amouda Venkatsan, MINING PLUTELLA XYLOSTELLA EXPRESSED SEQUENCE TAGS (EST) FOR A FUNCTIONALLY ANNOTATED CANDIDATE GENE INDEX. Indian journal of Agricultural Research, 201650 (1), 33-38.
5760. Sailu Sarvagalla, Hsing-Pang Hsieh and Mohane Selvaraj Coumar*THERAPEUTIC POLYMERIC NANOPARTICLES AND METHODS OF MAKING AND USING SAME: A PATENT EVALUATION OF WO2015036792Expert opinion Therapeutic Patents201626 (7), 751-755
56Syed, S. B.; Coumar, M. S.*P-GLYCOPROTEIN MEDIATED MULTIDRUG RESISTANCE REVERSAL BY PHYTOCHEMICALS: A REVIEW OF SAR & FUTURE PERSPECTIVE FOR DRUG DESIGN.Current topics in medicinal chemistry,201616(22), 2484-508.
55Sailu Sarvagalla and Mohane Selvaraj Coumar*PROTEIN-PROTEIN INTERACTIONS (PPIS) AS AN ALTERNATIVE TO TARGETING THE ATP BINDING SITE OF KINASE: IN SILICO APPROACH TO IDENTIFY PPI INHIBITORS inApplied Case Studies and Solutions in Molecular Docking-Based Drug Design, Eds.: Siavoush Dastmalchi, Maryam Hamzeh-Mivehround and Babak Sokouti, IGI Global, 2016pp249-277
54Kumaravel Mohankumar, Subhashree Sridharan, Sankar Pajaniradje, Vivek Kumar Singh, Larance Ronsard, Akhil C. Banerjea, Dinesh Babu Somasundaram, Mohane Selvaraj Coumar, Latha Periyasamy, Rukkumani RajagopalanBDMC-A, AN ANALOG OF CURCUMIN, INHIBITS MARKERS OF INVASION, ANGIOGENESIS, AND METASTASIS IN BREAST CANCER CELLS VIA NF-κb PATHWAY- A COMPARATIVE STUDY WITH CURCUMINBiomedicine & Pharmacotherapy201574, 178-186
53Ke, Y. Y.; Singh, V. K.; Coumar, M. S.; Hsu, Y. C.; Wang, W. C.; Song, J. S.; Chen, C. H.; Lin, W. H.; Wu, S. H.; Hsu, J. T.; Shih, C.; Hsieh, H. P., Homology modeling of DFG-in FMS-like tyrosine kinase 3 (FLT3) and structure-based virtual screening for inhibitor identification, Scientific Reports 20155:11702
52Gopichand Chinta, Mariasoosai Ramya Chandar Charles, Ivana Klopcic, Marija Sollner Dolenc, Latha Periyasamy,* and Mohane Selvaraj Coumar*IN SILICO AND IN VITRO INVESTIGATION OF THE PIPERINE'S MALE CONTRACEPTIVE EFFECT: DOCKING AND MOLECULAR DYNAMICS SIMULATION STUDIES IN ANDROGEN BINDING PROTEIN AND ANDROGEN RECEPTOR, Planta medica201581, 804-812
51Sailu Sarvagalla, Vivek Kumar Singh, Yi-Yu Ke, Hui-Yi Shiao, Wen-Hsing Lin, Hsing-Pang Hsieh, John T. A. Hsu, and Mohane Selvaraj Coumar*IDENTIFICATION OF LIGAND EFFICIENT, FRAGMENT-LIKE HITS FROM AN HTS LIBRARY: STRUCTURE-BASED VIRTUAL SCREENING AND DOCKING INVESTIGATIONS OF 2H- AND 3H-PYRAZOLO TAUTOMERS FOR AURORA KINASE A SELECTIVITYJ. Computuer Aided Molecular Design201529, 89-100
50Gopichand Chinta, Safiulla Basha Syed, Mohane Selvaraj Coumar, Latha PeriyasamyPIPERINE: A COMPREHENSIVE REVIEW OF PRE-CLINICAL AND CLINICAL INVESTIGATIONSCurrent Bioactive Compounds201511(3), 156-169
49Sailu Sarvagalla and Mohane Selvaraj Coumar*STRUCTURAL BIOLOGY INSIGHT FOR THE DESIGN OF SUB-TYPE SELECTIVE AURORA KINASE INHIBITORSCurrent Cancer Drug Targets.201515, 375-393
48R. Vasundhara Devi, S. Siva Sathya, Mohane Selvaraj Coumar*EVOLUTIONARY ALGORITHMS FOR DE NOVO DRUG DESIGN – A SURVEYApplied Soft Computing201527, 543-552
47Kumaravel Mohankumar, Sankar Pajaniradje, Subhashree Sridharan, Vivek Kumar Singh, Larance Ronsard, Akhil C Banerjea, Chellakkan S Benson, Mohane Selvaraj Coumar, Latha Periyasamy, Rajagopalan RukkumaniMOLECULAR MECHANISM OF APOPTOTIC INDUCTION BY AN ANALOG OF CURCUMIN, BDMC-A IN HUMAN LARYNGEAL CARCINOMA CELL LINE (HEP-2) THROUGH EXTRINSIC AND INTRINSIC PATHWAYS IN COMPARISON WITH CURCUMIN: AN IN VITRO - IN SILICO STUDYCellular Oncology201437,439-454
46Yi-Yu Ke, Mohane Selvaraj Coumar, Hui-Yi Shiao, Wen-Chieh Wang, Chieh-Wen Chen, Jen-Shin Song, Chun-Hwa Chen, Wen-Hsing Lin, Szu-Huei Wu, John T. A. Hsu, Chung-Ming Chang and Hsing-Pang HsiehLIGAND EFFICIENCY BASED APPROACH FOR EFFICIENT VIRTUAL SCREENING OF COMPOUND LIBRARIESEuropean J Medicinal Chemistry201483, 226-235
45Hemant Arya and Mohane Selvaraj Coumar*VIRTUAL SCREENING OF TRADITIONAL CHINESE MEDICINE (TCM) DATABASE: IDENTIFICATION OF FRAGMENT-LIKE LEAD MOLECULES FOR FILARIASIS TARGET ASPARAGINYL-TRNA SYNTHETASEJ. Molecular Modeling201420, 2266
44R. Vasundhara Devi, S. Siva Sathya, Mohane Selvaraj Coumar*MULTI-OBJECTIVE GENETIC ALGORITHM FOR DE NOVO DRUG DESIGNInternational J. Soft Computing Engineering20144 (2), 92-96
43Kumaravel Mohankumar, Sankar Pajaniradje, Subhashree Sridharan, Vivek Kumar Singh, Larance Ronsard, Akhil C Banerjea, Chellakkan S Benson, Mohane Selvaraj Coumar, Rukkumani Rajagopalan.MECHANISM OF APOPTOTIC INDUCTION IN HUMAN BREAST CANCER CELL, MCF-7, BY AN ANALOG OF CURCUMIN IN COMPARISON WITH CURCUMIN - AN IN VITRO AND IN SILICO APPROACHChemio-Biological. Interaction2014210, 51-63
42R. Vasundhara Devi, S. Siva Sathya and Mohane Selvaraj Coumar*.GAMOL: GENETIC ALGORITHM BASED DE NOVO MOLECULE GENERATORInt. Conf. on Adv. in Comp., Comm., and Inf. Sci. (ACCIS-14);
TKM College of Engineering, Kollam, Kerala, India, June 26-28th 2014
2014259-265
41Chun Hei Antonio Cheung, Sailu Sarvagalla, Jane Ying-Chieh Lee, Yi-Chun Huang, Mohane Selvaraj Coumar*AURORA KINASE INHIBITOR PATENTS AND AGENTS IN CLINICAL TESTING: AN UPDATE (2011-13)Expert opinion Therapeutic. Patents201424 (9), 1021-1038
40Hui-Yi Shiao, Mohane Selvaraj Coumar, Chun-Wei Chang, Yi-Yu Ke, Ya-Hui Chi, Chang-Ying Chu, Hsu-Yi Sun, Chun-Hwa Chen, Wen-Hsing Lin, Ka-Shu Fung, Po-Chu Kuo, Chin-Ting Huang, Kai-Yen Chang, Cheng-Tai Lu, John T. A. Hsu, Chiung-Tong Chen, Weir-Torn Jiaang, Yu-Sheng Chao, and Hsing-Pang HsiehOPTIMIZATION OF LIGAND AND LIPOPHILIC EFFICIENCY TO IDENTIFY AN IN VIVO ACTIVE FURANO-PYRIMIDINE AURORA KINASE INHIBITORJ. Medicinal Chemistry201356, 5247-5260
39Yi-Hui Peng, Hui-Yi Shiao, Chih-Hsiang Tu, Pang-Min Liu, John Tsu-An Hsu, Prashanth Kumar Amancha, Jian-Sung Wu, Mohane Selvaraj Coumar, Chun-Hwa Chen, Sing-Yi Wang, Wen-Hsing Lin, Hsu-Yi Sun, Yu-Sheng Chao, Ping-Chiang Lyu, Hsing-Pang Hsieh, and suying wuPROTEIN KINASE INHIBITOR DESIGN BY TARGETING THE ASP-PHE-GLY (DFG) MOTIF: THE ROLE OF THE DFG MOTIF IN THE DESIGN OF EPIDERMAL GROWTH FACTOR RECEPTOR INHIBITORSJ. Medicinal Chemistry201356, 3889−3903
38Jiun-Ming Wu, Chiung-Tong Chen, Mohane Selvaraj Coumar, Wen-Hsin Lin, Zi-Jie Chen, John T.-A. Hsu, Yi-Hui Peng, Hui-Yi Shiao, Wen-Hsing Lin, Chang-Ying Chu, Jian-Sung Wu, Chih-Tsung Lin, Ching-Ping Chen, Ching-Cheng Hsueh, Kai-Yen Chang, Li-Pin Kao, Chi-Ying F. Huang, Yu-Sheng Chao, Su-Ying Wu, Hsing-Pang Hsieh, and Ya-Hui ChiAURORA KINASE INHIBITORS REVEAL MECHANISMS OF HURP IN NUCLEATION OF CENTROSOMAL AND KINETOCHORE MICROTUBULESProceedings. National Academia Sciences USA2013110, E1779-E1787
37Yi-Yu Ke, Hui-Yi Shiao, Yung Chang Hsu, Chang-Ying Chu, Wen-Chieh Wang, Yen-Chun Lee, Wen-Hsing Lin, Chun-Hwa Chen, John T. A. Hsu, Chun-Wei Chang, Cheng-Wei Lin, Teng-Kuang Yeh, Yu-Sheng Chao, Mohane Selvaraj Coumar,* and Hsing-Pang Hsieh.*3D-QSAR ASSISTED DRUG DESIGN: IDENTIFICATION OF A POTENT QUINAZOLINE BASED AURORA KINASE INHIBITORChemMedChem20138, 136-148
36Mohane Selvaraj Coumar, Fang-Ying Tsai, Jagat Rakesh Kanwar, Sailu Sarvagalla, Chun Hei Antonio Cheung.TREAT CANCERS BY TARGETING SURVIVIN: JUST A DREAM OR FUTURE REALITY? Cancer Treatment Reviews201339, 802-811
35Jiann-Yih Yeh, Mohane Selvaraj Coumar, Hui-Yi Shiao, Ta-Jen Lin, Yen-Chun Lee, Hui-Chen Hung, Shengkai Ko, Fu-Ming Kuo, Ming-Yu Fang, Yu-Lin Huang, John T. A. Hsu, Teng-Kuang Yeh, Shin-Ru Shih, Yu-Sheng Chao, Jim-Tong Horng, and Hsing-Pang HsiehANTI-INFLUENZA DRUG DISCOVERY: IDENTIFICATION OF ORALLY BIOAVAILABLE QUINOLINE DERIVATIVE THROUGH ACTIVITY AND PROPERTY GUIDED LEAD OPTIMIZATIONChemMedChem20127, 1546-1550
34Chun Hei Antonio Cheung, Wen-Hsing Lin, John Tsu-An Hsu, Tzyh-Chyuan Hour, Teng-Kuang Yeh, Shengkai Ko, Tzu-Wen Lien, Mohane Selvaraj Coumar, Jin-Fen Liu, Wen-Yang Lai, Hui-Yi Shiao, Tian-Ren Lee, Hsing-Pang Hsieh, Jang-Yang ChangBPR1K653, A NOVEL AURORA KINASE INHIBITOR, EXHIBITS POTENT ANTI-PROLIFERATIVE ACTIVITY IN MDR1 (P-GP170)-MEDIATED MULTIDRUG-RESISTANT CANCER CELLSPLoS ONE20116(8): e23485
33Yen-Shih Tung, Mohane Selvaraj Coumar, Yu-Shan Wu, Hui-Yi Shiao, Jang-Yang Chang, Jing-Ping Liou, Paritosh Shukla, Chun-Wei Chang, Chi-Yen Chang, Ching-Chuan Kuo, Teng-Kuang Yeh, Chin-Yu Lin, Jian-Sung Wu, Su-Ying Wu,† Chun-Chen Liao, and Hsing-Pang HsiehSCAFFOLD-HOPPING STRATEGY: SYNTHESIS AND BIOLOGICAL EVALUATION OF 5,6-FUSED BICYCLIC–HETEROAROMATICS TO IDENTIFY ORALLY BIOAVAILABLE ANTICANCER AGENTSJ. Medicinal Chemistry201154, 3076-3080
32Chun Hei Antonio Cheung, Mohane Selvaraj Coumar, Jang-Yang Chang, Hsing-Pang HsiehAURORA KINASE INHIBITOR PATENTS AND AGENTS IN CLINICAL TESTING: AN UPDATE (2009-10)Expert opinion Therapeutic. Patents201121, 857-884
31Yi-Hui Peng, Mohane Selvaraj Coumar, Jiun-Shyang Leou, Jian-Sung Wu, Hui-Yi Shiao, Chia-Hui Lin, Wen-Hsin Lin, Tzu Wen Lien, Xin Chen, John T.-A. Hsu, Yu-Sheng Chao, Ping-Chiang Lyu, Hsing-Pang Hsieh and Su-Ying WuSTRUCTURAL BASIS FOR THE IMPROVED POTENCY OF PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR (PPAR) AGONISTSChemMedChem20105, 1707–1716
30Mohane Selvaraj Coumar, Chang-Ying Chu, Cheng-Wei Lin, Hui-Yi Shiao, Yun-Lung Ho, Randheer Reddy, Santhosh Kumar Chittimalla, Chun-Hwa Chen, Tzu-Wen Lien, Chin-Ting Huang, Wen-Hsing Lin, John T.-A. Hsu, Jiun-Shyang Leou, Yi-Hui Peng, Jian-Sung Wu, Su-Ying Wu, Chun-Chen Liao, Yu-Sheng Chao, and Hsing-Pang HsiehFAST-FORWARDING KINASE DRUG DISCOVERY: AURORA AND EGFR KINASE INHIBITOR LEAD IDENTIFICATIONJ. Medicinal Chemistry201053, 4980-4988
29Jiann-Yih Yeh, Mohane Selvaraj Coumar, Jim-Tong Horng,║ Hui-Yi Hsiao,║ Fu-Ming Kuo, Hui-Ling Lee, In-Chun Chen, Chun-Wei Chang, Sung-Nain Tseng, Shin-Ru Shih, John T.-A. Hsu, Chun-Chen Liao, Yu-Sheng Chao and Hsing-Pang HsiehANTI-INFLUENZA DRUG DISCOVERY: STRUCTURE-ACTIVITY RELATIONSHIP INSIGHT INTO NOVEL ANGELICIN DERIVATIVESJ. Medicinal Chemistry201053, 1519–1533
28Mohane Selvaraj Coumar, Ming-Tsung Tsai, Chang-Ying Chu, Biing-Jiun Uang, Chi-Huang Teng, Chun-Yu Chang, Teng-Yuan Chang, Wen-Hsing Lin, John T.-A. Hsu, Jian-Sung Wu, Su-Ying Wu, Yu-Sheng Chao, and Hsing-Pang HsiehIDENTIFICATION, SAR STUDIES AND X-RAY COCRYSTAL ANALYSIS OF A NOVEL FURANO-PYRIMIDINE AURORA KINASE A INHIBITORChemMedChem20105 (2), 255-267
27Chun Hei Antonio Cheung, Huang-Hui Chen, Ching-Chuan Kuo, Chi-Yen Chang, Mohane S. Coumar, Hsing-Pang Hsieh and Jang-Yang ChangSURVIVIN COUNTERACTS THE THERAPEUTIC EFFECT OF MICROTUBULE DE-STABILIZERS BY STABILIZING TUBULIN POLYMERSMolecular Cancer20098:43
26Yu-Shan Wu, Mohane Selvaraj Coumar, Jang-Yang Chang, Hsu-Yi Sun, Fu-Ming Kuo, Ching-Chuan Kuo, Ying-Jun Chen, Chi-Yen Chang, Chia-Ling Hsiao, Jing-Ping Liou, Ching-Ping Chen, Hsien-Tsung Yao, Yi-Kun Chiang, Uan-Kang Tan, Chiung-Tong Chen, Chang-Ying Chu, Su-Ying Wu, Teng-Kuang Yeh, Chin-Yu Lin and Hsing-Pang HsiehSYNTHESIS AND EVALUATION OF 3-AROYLINDOLES AS ANTICANCER AGENTS: METABOLITE APPROACHJ. Medicinal Chemistry200952 (15), 4941-4945
25Yi-Kun Chiang, Ching-Chuan Kuo, Yu-Shan Wu, Chiung-Tong Chen, Mohane Selvaraj Coumar, Jian-Sung Wu, Hsing-Pang Hsieh, Chi-Yen Chang, Huan-Yi Jseng, Ming-Hsine Wu, Jiun-Shyang Leou, Jen-Shin Song, Jang-Yang Chang, Ping-Chiang Lyu, Yu-Sheng Chao and Su-Ying WuGENERATION OF LIGAND-BASED PHARMACOPHORE MODEL AND VIRTUAL SCREENING FOR IDENTIFICATION OF NOVEL TUBULIN INHIBITORS WITH POTENT ANTICANCER ACTIVITYJ. Medicinal Chemistry200952 (14), 4221-4233
24Chia-Hui-Lin, Yi-Hui Peng, Mohane Selvaraj Coumar, Santhosh Kumar Chittimalla, Chin-Chieh Huang, Tzu-wen Lien, Wen-Hsin Lin, John T.-A. Hsu, Uan-Kang Tan, Jai-Hong Cheng, Xin Chen, Chun-Chen Liao, Ping-Chiang Lyn, Yu-Sheng Chao, Su-Ying Wu, and Hsing-Pang HsiehDESIGN AND STRUCTURAL ANALYSIS OF NOVEL PHARMACOPHORES FOR POTENT AND SELECTIVE PPAR AGONISTSJ. Medicinal Chemistry200952 (8), 2618-2622
23Mohane Selvaraj Coumar, Jiun-Shyang Leou, Paritosh Shukla, Jian-Sung Wu, Ajay Kumar Dixit, Wen-Hsing Lin, Chun-Yu Chang, Tzu-Wen Lien, Uan-Kang Tan, Chun-Hwa Chen, John T.-A. Hsu, Yu-Sheng Chao, Su-Ying Wu and Hsing-Pang HsiehSTRUCTURE-BASED DRUG DESIGN OF NOVEL AURORA KINASE A INHIBITORS: STRUCTURAL BASIS FOR POTENCY AND SPECIFICITYJ. Medicinal Chemistry200952 (4), 1050-1062
22Mohane Selvaraj Coumar, Chun Hei Antonio Cheung, Jang-Yang Chang, Hsing-Pang HsiehADVANCES IN AURORA KINASE INHIBITORS AND THEIR PATENTSExpert opinion Therapeutic. Patents200919 (3), 321-356
21Chun Hei Antonio Cheung, Mohane Selvaraj Coumar, Jang-Yang Chang, Hsing-Pang HsiehAURORA KINASE INHIBITORS IN PRECLINICAL AND CLINICAL TESTINGExpert opinion Investigational Drugs200918(4), 379-398
20Gadarla Randheer Reddy, Ching-Chuan Kuo, Uan-Kang Tan, Mohane Selvaraj Coumar, Chi-Yen Chang, Chiang Yi-Kun, Su-Ying Wu, Jang-Yang Chang, Jing-Ping Liou and Hsing-Pang HsiehSYNTHESIS AND STRUCTURE-ACTIVITY RELATIONSHIPS OF 2-AMINO AND 2-HYDROXY-1-AROYLNAPHTHALENES AS POTENT ANTITUBULIN AGENTSJ. Medicinal Chemistry200851, 8163-8167
19Mohane S. Coumar*, Dharam P. Jindal, Giancarlo Bruni, Paola Massarelli, Randhir Singh, Amit K. Sharma, K. Nandakumar and Subhash L. BodhankarSYNTHESIS, Β-ADRENERGIC RECEPTOR BINDING AND ANTIHYPERTENSIVE POTENTIAL OF VANILLIN-DERIVED PHENOXY PROPANOLAMINESIndian J Chemistry200847B(6), 903-909
18Mohane Selvaraj Coumar, Jian-Sung Wu, Jiun-Shyang Leou, Uan-Kang Tan, Chung-Yu Chang, Teng-Yuan Chang, Wen-Hsing Lin, John T.-A. Hsu, Yu-Sheng Chao, Su-Ying Wu and Hsing-Pang HsiehAURORA KINASE A INHIBITORS: IDENTIFICATION, SAR EXPLORATION AND MOLECULAR MODELING OF 6,7-DIHYDRO-4H-PYRAZOLO[1,5-A]PYRROLO[3,4-D]PYRIMIDINE-5,8-DIONE SCAFFOLDBioorganic Medicinal Chemistry Letters200818, 1623-1327
17Mohane Selvaraj Coumar, Chung-Nien Chang, Chiung-Tong Chen, Xin Chen, Chia-Hui Chien, Ting-Yueh Tsai, Jai-Hong Cheng, Hsin-Yi Wu, Chia-Hung Han, Ssu-Hui Wu, Yu-Wen Huang, Tsu Hsu, Yu-Sheng Chao, Hsing-Pang Hsieh and Weir-Torn Jiaang3-[2-((2S)-2-CYANO-PYRROLIDIN-1-YL)-2-OXO-ETHYLAMINO]-3-METHYL-BUTYRAMIDE ANALOGUES AS SELECTIVE DPP-IV INHIBITORS FOR THE TREATMENT OF TYPE-II DIABETESBioorganic Medicinal Chemistry Letters200717, 1274-1279
16Ting-Yueh Tsai, Mohane S. Coumar, Tsu Hsu, Hsing-Pang Hsieh, Chia-Hui Chien, Chiung-Tong Chen, Chung-Nien Chang, Yu-Kang Lo, Ssu-Hui Wu, Chung-Yu Huang, Yu-Wen Huang, Min-Hsien Wang, Hsin-Yi Wu, Hong-Jen Lee, Xin Chen, Yu-Sheng Chao and Weir-Torn JiaangSUBSTITUTED PYRROLIDINE-2,4-DICARBOXYLIC ACID AMIDES AS POTENT DIPEPTIDYL PEPTIDASE IV INHIBITORSBioorganic Medicinal Chemistry Letters200616, 3268-3272
15Hsu Tsu, Xin Chen, Chiung-Tong Chen, Shiow-Ju Lee, Chung-Nien Chang, Kuo-His Kao, Mohane S. Coumar, Yen-Ting Yeh, Chia-Hui Chien, Hsin-Sheng Wang, Ke-Ta Lin, Ying-Ying Chang, Ssu-Hui Wu, Yuan-Shou Chen, I-Lin Lu, Su-Ying Wu, Ting-Yueh Tsai, Wei-Cheng Chen, Hsing-Pang Hsieh, Yu-Sheng Chao, Weir-Torn Jiaang2-[3-[2-[(2S)-2-CYANO-1-PYRROLIDINYL]-2-OXOETHYLAMINO]-3-METHYL-1-OXOBUTYL]-1,2,3,4-TETRAHYDROISOQUINOLINE: A POTENT, SELECTIVE, AND ORALLY BIOAVAILABLE DIPEPTIDE-DERIVED INHIBITOR OF DIPEPTIDYL PEPTIDASE IVJ. Medicinal Chemistry200649, 373-380
14Nandakumar, K., Singh, R., Sharma, A., Sharma, B., Bodhankar, S.L., Coumar, M.S., Jindal, D.PEFFECT OF TWO NEWLY SYNTHESIZED β BLOCKERS, DPJ 955 AND DPJ 890 ON ECG OF ANAESTHETIZED MICEIndian Drugs200643, 481-485
1332. Dharam Paul Jindal, Babita Singh, Mohane S. Coumar*, Giancarlo Bruni and Paola MassarelliSYNTHESIS OF 4-(1-OXO-ISOINDOLINE) AND 4-(5,6-DIMETHOXY-1-OXO-ISOINDOLINE)-SUBSTITUTED PHENOXYPROPANOLAMINES AND THEIR BETA1-, BETA2-ADRENERGIC RECEPTOR BINDING STUDIESBioorgani Chemistry200533, 310-324
12Dharam Paul Jindal, Babita Singh, Mohane S. Coumar*, Giancarlo Bruni and Paola MassarelliSYNTHESIS OF 4-(PHTHALIMIDE) AND 4-(BENZAMIDE)-SUBSTITUTED PHENOXYPROPANOLAMINES AND THEIR 1, 2-ADRENERGIC RECEPTOR BINDING STUDIESIndian J. Chemistry200544B, 1441-1445
11Nandakumar K, Bansal SK, Singh R, Bodhankar SL, Jindal DP, Coumar MS, Balaraman R, Bhardwaj SHSELECTIVE BETA(1)-ADRENORECEPTOR BLOCKING ACTIVITY OF NEWLY SYNTHESIZED ACYL AMINO-SUBSTITUTED ARYLOXYPROPANOLAMINE DERIVATIVES, DPJ 955 AND DPJ 890, IN RATSJ Pharmacy Pharmacology200557, 515-519
10K. Nandakumar, S.K. Bansal, Randhir Singh, A.J. Mohite, S.L. Bodhankar, D.P. Jindal, Mohane S. Coumar, R. Balaraman, S.H. BhardwajSTUDY OF  ADRENORECEPTOR ANTAGONISTIC ACTIVITY OF DPJ 904 IN RATSPharmacology200574, 1-5
9Nandakumar K, Bansal S, Bhatt LK, Bodhankar SL, Ghole VS, Coumar MS, Jindal DPCARDIOPROTECTIVE EFFECT OF NEWLY SYNTHESIZED ACYL AMINO SUBSTITUTED PROPANOLAMINE DERIVATIVES, DPJ 955 AND DPJ 890 AGAINST ISOPRENALINE INDUCED MYOCARDIAL NECROSISToxicology International,200510 12(2), 61-66
8Nandakumar K, Singh R, Bansal SK, Bodhankar SL, Jindal DP, Coumar MS, Bhardwaj SH ANTIHYERTENSIVE EFFECT OF NEWLY SYNTHETIZED ACYLAMINO PROPRANOLAMINE DERIVATIVES, DPJ 890 AND DPJ 955 IN HYPERTENSIVE RATSIndian J. Pharmcology200436(6), 381-382
7Sunil Bajad, Mohane S. Coumar, Ravi K. Khajuria, Om P. Suri, Kasturi L. Bedi.CHARACTERIZATION AND SYNTHESIS OF A NEW URINARY METABOLITE 5-[3,4-METHELENEDIOXYPHENYL]-2E,4E-PENADIENOIC ACID-N-(3-YL-PROPIONIC ACID)]-AMIDE OF PIPERINE, AN OMNIPRESENT FOOD COMPONENT, BY LC/NMR/MSEuropean. J. Pharmaceutical Sciences200319, 413–421
6Dharam Paul Jindal, Mohane S. Coumar, Nandakumar K, Subhash Laxmanrao Bodhankar, Prasad Gopal Purohit, Kakasaheb Ramoo Mahadik, Giancarlo Bruni, Elga Collavoli and Paola MassarelliSYNTHESIS, -ADRENERGIC BLOCKING ACTIVITY AND -RECEPTOR BINDING AFFINITIES OF 1-SUBSTITUTED-3-(2-ISOPROPYL-5-METHYL-PHENOXY)-PROPAN-2-OL OXALATESIl Farmaco200358(8), 557-562
5Dharam Paul Jindal, Mohane S. Coumar, Babita Singh, Mohammed Muhiyiden M.I., Girish Nilkanth Zambare and Subhash Laxmanrao BodhankarSYNTHESIS AND LOCAL ANAESTHETIC ACTIVITY OF 2-SUBSTITUTED-N-(2-DIETHYLAMINOETHYL)-ACETAMIDESArzneimittel Forschung/Drug Research, 2003 53(1), 34-39
4Dharam Paul Jindal, Babita Singh, Mohane S. Coumar*, Giancarlo Bruni and Paola Massarelli.SYNTHESIS OF 4-(1-OXO-ISOINDOLINE)-, 4-(5,6-DIMETHOXY-1-OXO-ISOINDOLINE)-AND 4-ACETAMIDO-SUBSTITUTED PHENOXY-3-AMINO-PROPANEDERIVATIVES AND THEIR 1-, 2-ADRENERGIC RECEPTOR BINDING STUDIESIndian J. Chemistry 200342B(11), 2808
3Dharam Paul Jindal, Mohane S. Coumar, Giancarlo Bruni and Paola Massarelli., SYNTHESIS AND ?1-, ?2-ADRENERGIC RECEPTOR BINDING STUDIES OF 4-ACYLAMINO SUBSTITUTED PHENOXYPROPANOLAMINE AND 5-ACYLAMINO SUBSTITUTED NAPHTHYLOXY PROPANOLAMINE DERIVATIVES, , Arzneimittel Forschung/Drug Research, 2002Arzneimittel Forschung/Drug Research, 200252(9), 654-663
2G. Vasuki, V. Parthasarathi, K. Ramamurthi, S. Mohane Coumar, and D.P.Jindal, 2-(1H-INDOL-3-YLMETHYLENE)INDANE-1-ONE, , Acta Crystallographica, 2002Acta Crystallographica, 2002E58, o1222–o1223
1G. Vasuki, S. Thamotharan, V. Parthasarathi, K. Ramamurthi, S. Mohane Coumar, and D.P.Jindal,N-(TERT-BUTYL)-N-[2-HYDROXY-3-(2-ISOPRPYL-5-METHYLPHENOXY)PROPYL]AMMONIUM HYDROGEN OXALATEActa Crystallographica, 2002E58, o93-o94

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